Competitors do not need to register in advance but simply arrive at Chirk Basin, near Wrexham, on the day of the race from 10.30am and register their name against a duck number.
Chirk's stunning 70 feet high aqueduct, built by Thomas Telford more than 200 years ago, marks the boundary between England and Wales and is part of the Trust's impressive 11mile Pontcysyllte Aqueduct and Llangollen Canal World Heritage Site.
The event, jointly organised by Wrexham County Council, is free but competitors will be invited to make a donation to the well-being and waterways charity Canal & River Trust, which cares for 2,000 miles of the nation's canals, and Nightingale House Hospice, which provides the ducks.